Malaria Prevention And Treatment #Summary

Contents

(1)👹👹SEVER and COMPLICATED;:(for specific cases)

#Malaria_prevention
We have to know drugs names first
*Artesunate
*proguanil
*Quinine
*CloroQuine
*primaquine

Then we have to know when and how to choose the drug according to the case::

(1)👹👹SEVER and COMPLICATED;:(for specific cases)

** Artesunate / IV 2.4 mg/kg at 0, 12 and 24 hours

When the patient is well enough to take oral medication 🆗 give:
**Artesunate /oral 2 mg/kg (or IM artesunate 2.4 mg/kg) once daily, plus clindamycin.

If oral artesunate is not available, use :
**3-day course of Riamet®Proguanil or/
** 7-day course of quinine and clindamycin at 450mg(3 times a day 7 days).

ALTERNATIVELY⏰

**Quinine /IV 20 mg/kg loading dose (no loading dose if patient already taking quinine or mefloquine) in 5% dextrose over 4 hours .
then
**10 mg/kg IV over 4 hours every 8 hours plus clindamycin IV 450 mg every 8 hours.
When the patient is well enough to take oral medication🆗
switch to**Quinine/oral/600 mg 3 times a day to complete 5–7 days and oral **clindamycin/450 mg 3 times a day 7 days .

(2):Uncomplicated malaria🍀🍀

##P. falciparum ##
**Oral quinine 600 mg 8 hourly + oral clindamycin 450 mg 8 hourly.for 7 days .
OR
**Atovaquone-Proguanil (Malarone®) 4 standard tablets daily /for 3 days.

##Vomiting##but no signs of severe or complicated Malaria:

**Quinine 10 mg/kg dose IV in 5% dextrose over 4 hours every 8 hours.
+**clindamycin /IV/450 mg every 8 hours.

When the patient is well🆗:

**Quinine/oral/600 mg 3 times a day to complete 5–7 days + **clindamycin /Oral.

(3)Non-falciparum Malaria:☕☕

##P. vivax,##
## P. ovale##
##, P. malariae##
**chloroquine** /Oral/600 mg followed by 300 mg 68 hours later
Then 300 mg on day 2 and again on day 3

##Resistant P. vivax##🔜
As for uncomplicated malaria P. falciparum.

##Preventing relapse DURING pregnancy##🌷🌷
**Chloroquine oral 300 mg weekly until delivery.

##Preventing relapse AFTER delivery##🌷🌷
Chloroquine oral 300 mg weekly until delivery and Postpone until 3 months after delivery and G6PD testing.

##P. Ovale##🍒